Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29021977 | 0.85 | FOLH1 (0.54) | CYP2C9TSHRLMNAALOX15CYP2C19 | |
| SCHEMBL13692320 | 0.85 | CYP2C9 (0.53) | CYP2C9TSHRLMNAALOX15CYP2C19 | |
| SCHEMBL30687339 | 0.85 | CYP2C9 (0.53) | CYP2C9TSHRLMNAALOX15CYP2C19 | |
| SCHEMBL2308742 | 0.85 | CYP2C9 (0.53) | CYP2C9TSHRLMNACYP2C19HPGD | |
| SCHEMBL11482363 | 0.84 | CYP2C9 (0.60) | CYP2C9TSHRLMNAALOX15CYP2C19 | |
| Hydrochloric Acid SCHEMBL28152222 | 0.83 | CYP2C9 (0.51) | CYP2C9TSHRLMNACYP2C19HPGD | |
| SCHEMBL13687538 | 0.82 | CYP2C9 (0.50) | CYP2C9TSHRCYP2C19HPGDMEN1 | |
| SCHEMBL30505689 | 0.79 | CYP2C9 (0.50) | CYP2C9TSHRLMNACYP2C19HPGD | |
| SCHEMBL69352 | 0.79 | TSHR (0.68) | CYP2C9TSHRALOX15FOLH1HPGD | |
| SCHEMBL17938486 | 0.77 | TSHR (0.66) | CYP2C9TSHRALOX15FOLH1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285520-A | Medical use of carboxamide derivative, carboxamide derivative and pharmaceutical composition containing carboxamide derivative | 上海科技大学 | 2023-12-26 | — | — | CN | disclosed |
| EP-2828904-B1 | CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES | RAYNERGY TEK INC (TW) | 2019-06-12 | — | — | EP | disclosed |
| EP-2828903-B1 | OPTOELECTRONIC DEVICES COMPRISING POLYMERIC BLENDS | RAYNERGY TEK INC (TW) | 2017-11-01 | — | — | EP | disclosed |
| CN-102083836-B | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX INC | 2015-01-28 | — | — | CN | disclosed |
| US-20130295261-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2013-11-07 | — | — | US | disclosed |
| US-8420145-B2 | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| CN-102083836-A | Isosorbide derivatives and their use as flavor modifiers, tastants, and taste enhancers | SENOMYX INC | 2011-06-01 | — | — | CN | disclosed |
| EP-2254891-A2 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-2009111447-A2 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | SENOMYX, INC. | 2009-09-03 | — | — | US | disclosed |
| WO-2008041088-A2 | N-HYDROXY BENZAMIDES WITH ANTITUMOR ACTIVITY | EOS (ETHICAL ONCOLOGY SCIENCE) S.P.A. (IT) | 2008-04-10 | — | — | WO | disclosed |
| EP-1908751-A1 | N-hydroxy benzamides with antitumour activity | EOS S.p.A. (IT) | 2008-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220662-A1 | ISOSORBIDE DERIVATIVES AND THEIR USE AS FLAVOR MODIFIERS, TASTANTS, AND TASTE ENHANCERS | TAS2R10, TAS2R41, TAS2R30 | CYP2C9 1829/4885TSHR 1685/4885LMNA 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.