Terephthalamide

Terephthalamide

SCHEMBL28633601

CCCCCCCCCCC(N)=O.NC(=O)c1ccc(C(N)=O)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
APAF1 O14727 1/20 0.59
RGS12 O14924 1/20 0.59
HSP90AA1 P07900 1/20 0.59
MAPK1 P28482 1/20 0.59
SOAT1 P35610 2/20 0.55
FAAH O00519 1/20 0.55
TP53 P04637 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2C19 P33261 1/20 0.55
HSD17B3 P37058 6/20 0.55
KDM4E B2RXH2 2/20 0.55
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
PARP10 Q53GL7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalamide SCHEMBL28497793 0.92 MEN1 (0.67) MEN1KMT2AAPAF1RGS12HSP90AA1
Terephthalamide SCHEMBL28398318 0.92 MEN1 (0.67) MEN1KMT2AAPAF1RGS12HSP90AA1
Dodecane SCHEMBL9222476 0.92 MEN1 (0.67) MEN1KMT2AAPAF1RGS12HSP90AA1
Terephthalamide SCHEMBL17074059 0.92 MEN1 (0.67) MEN1KMT2AAPAF1RGS12HSP90AA1
Tetradecane SCHEMBL9312928 0.92 MEN1 (0.67) MEN1KMT2AAPAF1RGS12HSP90AA1
Octadecanoic Acid Amide SCHEMBL29012582 0.91 CES2 (0.62) MEN1KMT2AAPAF1RGS12HSP90AA1
Terephthalamide SCHEMBL28425925 0.89 PARP10 (0.50) MEN1KMT2AAPAF1RGS12HSP90AA1
Terephthalamide SCHEMBL5692269 0.87 PARP1 (0.52) MEN1KMT2ACYP3A4CYP2C19PARP10
Octadecanoic Acid Amide SCHEMBL31472279 0.86 TP53 (0.59) MEN1KMT2ASOAT1FAAHTP53
Terephthalic Acid SCHEMBL27926620 0.85 TP53 (0.57) MEN1KMT2ASOAT1FAAHTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112788991-A Sensor for measuring biopotentials URGO技术公司 2021-05-11 CN disclosed