Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | APAF1 | O14727 | 1/20 | 0.67 |
| ▸ | RGS12 | O14924 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.67 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecane SCHEMBL9222476 | 1.00 | MEN1 (0.67) | MEN1MAPK1KMT2AAPAF1RGS12 | |
| Terephthalamide SCHEMBL17074059 | 1.00 | MEN1 (0.67) | MEN1MAPK1KMT2AAPAF1RGS12 | |
| Terephthalamide SCHEMBL28497793 | 1.00 | MEN1 (0.67) | MEN1MAPK1KMT2AAPAF1RGS12 | |
| Terephthalamide SCHEMBL28398318 | 1.00 | MEN1 (0.67) | MEN1MAPK1KMT2AAPAF1RGS12 | |
| Terephthalamide SCHEMBL28633601 | 0.92 | MEN1 (0.59) | MEN1MAPK1KMT2AAPAF1RGS12 | |
| Decane SCHEMBL28230778 | 0.89 | MAPT (0.67) | MEN1MAPK1KMT2AAPAF1RGS12 | |
| SCHEMBL75644 | 0.88 | THRA (0.65) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL13617729 | 0.88 | THRA (0.65) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6835676 | 0.88 | THRA (0.65) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1327143 | 0.88 | THRA (0.65) | MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276131-A | Preparation of polyamide from arylene cyclic diamide | ALLIED SIGNAL INC. (US) | 1994-01-04 | — | — | US | disclosed |