SCHEMBL28633624

SCHEMBL28633624

COC(=O)C1(c2ccccc2-c2ccccc2)C=CC=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
MAPT P10636 2/20 0.36
ITGA4 P13612 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
THRB P10828 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
POLB P06746 4/20 0.33
LMNA P02545 4/20 0.33
KDM4E B2RXH2 4/20 0.33
HTT P42858 3/20 0.33
HPGD P15428 3/20 0.33
GAA P10253 2/20 0.33
HSD17B10 Q99714 2/20 0.33
FGFR1 P11362 1/20 0.33
SRC P12931 1/20 0.33
FGFR2 P21802 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238941 0.85 THRB (0.42) ALDH1A1MEN1KMT2ATHRBTDP1
SCHEMBL4225395 0.78 HDAC4 (0.42) ALDH1A1POLBLMNAGAA
SCHEMBL6421730 0.71 SLC6A2 (0.40) ALDH1A1THRBTDP1SLC6A2SLC6A4
SCHEMBL7287457 0.71 CA12 (0.36) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL17797042 0.70 SLC6A2 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL9442070 0.70 MEN1 (0.38) ALDH1A1MEN1KMT2AHTT
SCHEMBL28755670 0.69 HDAC4 (0.39) THRBTDP1
SCHEMBL28881197 0.69 CA1 (0.41) ALDH1A1MAPTMEN1KMT2ATDP1
SCHEMBL4413275 0.68 ALDH1A1 (0.34) ALDH1A1THRBTDP1SLC6A2SLC6A4
SCHEMBL17727866 0.68 ALDH1A1 (0.34) ALDH1A1THRBTDP1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113383054-A Material for organic electroluminescent device 默克专利有限公司 2021-09-10 CN disclosed