SCHEMBL28633738

SCHEMBL28633738

B.C=CCc1nc2ccccc2[nH]1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDAH1 O94760 1/20 0.58
POLB P06746 1/20 0.58
GAA P10253 1/20 0.54
NPC1 O15118 4/20 0.53
RAB9A P51151 4/20 0.53
BCHE P06276 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
PKM P14618 1/20 0.51
TP53 P04637 1/20 0.50
TSHR P16473 1/20 0.50
PDE10A Q9Y233 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
ALDH1A1 P00352 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463268 0.98 DDAH1 (0.59) DDAH1POLBGAANPC1RAB9A
Phosphine SCHEMBL28188475 0.96 DDAH1 (0.58) DDAH1POLBGAANPC1RAB9A
Hydrogen Sulfide SCHEMBL29094907 0.96 DDAH1 (0.58) DDAH1POLBGAANPC1RAB9A
Iodide SCHEMBL29040436 0.96 DDAH1 (0.58) DDAH1POLBGAANPC1RAB9A
Biphenyl SCHEMBL28917228 0.92 GAA (0.54) DDAH1POLBGAANPC1RAB9A
Carbamic Acid SCHEMBL7194349 0.88 CHRM1 (0.56) DDAH1POLBGAANPC1RAB9A
Quinoline SCHEMBL28872941 0.86 NPC1 (0.50) DDAH1POLBGAANPC1RAB9A
SCHEMBL10350115 0.83 SMN1; SMN2 (0.51) DDAH1POLBGAANPC1RAB9A
SCHEMBL8322003 0.81 POLB (0.66) DDAH1POLBGAANPC1RAB9A
SCHEMBL14128454 0.80 DDAH1 (0.65) DDAH1POLBGAANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110117299-B Rhodium complex containing ortho-carbon boron alkyl benzimidazole structure and preparation and application thereof 上海应用技术大学 2021-05-11 CN disclosed
CN-110117299-B Rhodium complex containing ortho-carbon boron alkyl benzimidazole structure and preparation and application thereof 上海应用技术大学 2021-05-11 CN disclosed