Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL230157 | 0.83 | POLB (0.84) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL833457 | 0.83 | POLB (0.66) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL9302629 | 0.83 | POLB (0.66) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL463268 | 0.82 | DDAH1 (0.59) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL9113349 | 0.82 | POLB (0.60) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL28633738 | 0.81 | DDAH1 (0.58) | POLBNPC1RAB9ADDAH1PDE10A | |
| Hydrogen Sulfide SCHEMBL29094907 | 0.81 | DDAH1 (0.58) | POLBNPC1RAB9ADDAH1CHRM1 | |
| Iodide SCHEMBL29040436 | 0.81 | DDAH1 (0.58) | POLBNPC1RAB9ADDAH1CHRM1 | |
| Phosphine SCHEMBL28188475 | 0.81 | DDAH1 (0.58) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL293402 | 0.80 | POLB (0.72) | POLBNPC1RAB9ADDAH1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10245684-A | — | — | None | — | — | JP | disclosed |
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| JP-H10245684-A | SURFACE TREATING AGENT FOR COPPER AND COPPER ALLOY | SHIKOKU CHEM CORP | 1998-09-14 | — | — | JP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |
| US-5173130-A | Immersing copper or alloy to be soldered in an aqueous solution containing a 2-alkylbenzimidazole and an organic acid to form a corrosion and heat resistant protective coating | SHIKOKU CHEMICALS CORPORATION (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0428383-A1 | Process for surface treatment of copper and copper alloy | SHIKOKU CHEMICALS CORPORATION (JP) | 1991-05-22 | — | — | EP | disclosed |