Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 3/20 | 0.53 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647285 | 0.82 | PDCD1 (0.42) | PDCD1CD274KDM4EALDH1A1 | |
| SCHEMBL18705900 | 0.77 | SLC6A4 (0.42) | GAAPOLBALDH1A1MAPT | |
| SCHEMBL18765477 | 0.77 | PDCD1 (0.63) | PDCD1CD274MEN1KMT2AKDM4E | |
| SCHEMBL220727 | 0.73 | HTT (0.48) | KDM4EHTTALDH1A1MAPT | |
| SCHEMBL27082631 | 0.69 | PDCD1 (0.54) | PDCD1CD274MEN1KMT2AKDM4E | |
| SCHEMBL21603925 | 0.69 | TSHR (0.56) | PDCD1CD274MEN1KMT2AKDM4E | |
| SCHEMBL21603927 | 0.69 | TSHR (0.56) | PDCD1CD274MEN1KMT2AKDM4E | |
| SCHEMBL695065 | 0.68 | MEN1 (0.68) | MEN1KMT2AGAAPOLBALDH1A1 | |
| SCHEMBL25609125 | 0.68 | MEN1 (0.57) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL375334 | 0.68 | ALDH1A1 (0.48) | PDCD1CD274MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776377-B | Indoline compound and preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | disclosed |