Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28633783 | 0.82 | PDCD1 (0.53) | PDCD1CD274KDM4EALDH1A1 | |
| SCHEMBL16462107 | 0.71 | CYP2A13 (0.61) | KDM4EALDH1A1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5554033 | 0.71 | MEN1 (0.45) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14742233 | 0.70 | BCHE (0.42) | CYP2D6CYP2C9CYP2C19KDM1APABPC1 | |
| SCHEMBL32675243 | 0.70 | CYP2A13 (0.44) | PDCD1CD274OPRL1ALDH1A1CYP2D6 | |
| SCHEMBL32675241 | 0.70 | CYP2A13 (0.44) | PDCD1CD274OPRL1ALDH1A1CYP2D6 | |
| SCHEMBL14848246 | 0.68 | ACHE (0.54) | PDCD1CD274OPRM1OPRK1 | |
| SCHEMBL7251009 | 0.67 | HRH3 (0.31) | KDM4EPABPC1 | |
| SCHEMBL18817927 | 0.65 | ALDH1A1 (0.34) | ALDH1A1CYP1A2 | |
| SCHEMBL2466537 | 0.65 | ACHE (0.47) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776377-B | Indoline compound and preparation method and application thereof | 沈阳药科大学 | 2021-08-24 | — | — | CN | disclosed |