Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647437 | 0.85 | BCHE (0.51) | BCHEADRB2OPRK1GAAMEN1 | |
| SCHEMBL28388774 | 0.85 | ADRB2 (0.59) | ADRB2GAA | |
| SCHEMBL27226219 | 0.85 | SIGMAR1 (0.53) | BCHEADRB2OPRK1TEAD1GAA | |
| SCHEMBL29259963 | 0.83 | BCHE (0.50) | BCHEADRB2OPRK1GAAMEN1 | |
| SCHEMBL186785 | 0.83 | BCHE (0.67) | BCHEOPRK1GAAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL22587709 | 0.82 | BCHE (0.65) | BCHEOPRK1GAAMEN1KMT2A | |
| SCHEMBL27227087 | 0.79 | SIGMAR1 (0.55) | BCHEDRD4KDM4EALDH1A1 | |
| SCHEMBL3401970 | 0.78 | BCHE (0.61) | BCHEOPRK1GAAMEN1KMT2A | |
| SCHEMBL28650414 | 0.77 | BCHE (0.45) | BCHEADRB2OPRK1GAAMEN1 | |
| SCHEMBL28650051 | 0.77 | BCHE (0.45) | BCHEADRB2OPRK1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454086-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-28 | — | — | CN | disclosed |