SCHEMBL2037916

SCHEMBL2037916

NCc1c[nH]c(=O)[nH]c1=O

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ DPYD Q12882 1/20 0.46
▸ GAA P10253 1/20 0.46
▸ ATAD2 Q6PL18 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ LMNA P02545 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ CYP19A1 P11511 1/20 0.46
▸ TSHR P16473 1/20 0.46
▸ THPO P40225 1/20 0.46
▸ MTOR P42345 1/20 0.46
▸ HTT P42858 1/20 0.46
▸ HBB P68871 1/20 0.46
▸ PMP22 Q01453 1/20 0.46
▸ SMN1; SMN2 Q16637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22659843 0.98 DPYD (0.45) DPYDGAAATAD2ALDH1A1LMNA
SCHEMBL28633880 0.90 GAA (0.44) DPYDGAAMAPT
SCHEMBL2320491 0.83 ALDH1A1 (0.48) DPYDGAAATAD2ALDH1A1LMNA
SCHEMBL5800398 0.81 — —
SCHEMBL4353311 0.81 DPYD (0.50) DPYDGAAATAD2ALDH1A1LMNA
SCHEMBL7599681 0.79 ALDH1A1 (0.45) DPYDGAAATAD2ALDH1A1LMNA
SCHEMBL161148 0.79 ATAD2 (0.54) DPYDGAAATAD2ALDH1A1LMNA
SCHEMBL18640304 0.78 KMT2A (0.50) GAAALDH1A1MAPT
SCHEMBL31326250 0.78 MPO (0.31) —
SCHEMBL2584919 0.77 LMNA (0.52) DPYDGAAATAD2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106525546-B Analysis method for modifying foam plastic enriched gold by using improved 5-aminomethyl uracil 中国科学院地质与地球物理研究所 2020-01-03 — — CN claimed
US-8802645-B2 Molecule for treating an inflammatory disorder PROSENSA TECHNOLOGIES B.V. (NL) 2014-08-12 — — US claimed
EP-0898575-B1 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT DR (US) 2004-12-29 — — EP claimed
US-20030194741-A1 COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES CAPROTEC BIOANALYTICS GMBH (DE) 2003-10-16 — — US claimed
US-20030054410-A1 Combinatorial protecting group strategy for multifunctional molecules CAPROTEC BIOANALYTICS GMBH (DE) 2003-03-20 — — US claimed
EP-0898575-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KÖSTER, Hubert (US) 1999-03-03 — — EP claimed
WO-1997041139-A2 A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES KOESTER HUBERT (US) 1997-11-06 — — WO claimed
US-20260146249-A1 ANTISENSE OLIGONUCLEOTIDES FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH AN ABNORMAL PROCESSING OF APP VICO THERAPEUTICS B.V. (NL) 2026-05-28 — — US disclosed
WO-2026099473-A1 OLIGONUCLEOTIDES WITH NEW INTERNUCLEOSIDE LINKAGE VICO THERAPEUTICS B.V. (NL) 2026-05-15 — — WO disclosed
EP-4728071-A1 ANTISENSE OLIGONUCLEOTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASE ProQR Therapeutics II B.V. (NL) 2026-04-22 — — EP disclosed
EP-4713459-A2 ANTI-VISTA ANTIBODY RNA OR NUCLEIC ACID CONJUGATES (ARCS OR ANCS), COMPOSITIONS CONTAINING, AND THERAPEUTIC USE THEREOF LIFORDI IMMUNOTHERAPEUTICS, INC. (US) 2026-03-25 — — EP disclosed
EP-4702143-A2 COMPOSITIONS AND METHODS FOR TREATING STXBP1 DISORDERS BioMarin Pharmaceutical Inc. (US) 2026-03-04 — — EP disclosed
EP-4702144-A1 ANTISENSE OLIGOMERS FOR TREATMENT OF CHRONIC KIDNEY DISEASE Sarepta Therapeutics, Inc. (US) 2026-03-04 — — EP disclosed
US-7101883-B2 Uracil derivatives as inhibitors of TNF-α converting enzyme (TACE) and matrix metalloproteinases BRISTOL-MYERS SQUIBB COMPANY (US) 2006-09-05 — — US disclosed
US-20030229081-A1 Uracil derivatives as inhibitors of TNF-alpha converting enzyme (TACE) and matrix metalloproteinases BRISTOL-MYERS SQUIBB COMPANY 2003-12-11 — — US disclosed
WO-2003079986-A2 URACIL DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND MATRIX METALLOPROTEINASES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-10-02 — — WO disclosed
WO-2003079986-A2 URACIL DERIVATIVES AS INHIBITORS OF TNF-ALPHA CONVERTING ENZYME (TACE) AND MATRIX METALLOPROTEINASES BRISTOL-MYERS SQUIBB COMPANY (US) 2003-10-02 — — WO disclosed
EP-1047705-A2 NUCLEOBASE OLIGOMERS THE PERKIN-ELMER CORPORATION (US) 2000-11-02 — — EP disclosed
US-6054568-A Nucleobase oligomers THE PERKIN-ELMER CORPORATION (US) 2000-04-25 — — US disclosed
WO-1999036429-A2 NUCLEOBASE OLIGOMERS THE PERKIN-ELMER CORPORATION (US) 1999-07-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030229081-A1 Uracil derivatives as inhibitors of TNF-alpha converting enzyme (TACE) and matrix metalloproteinases UNG, IDUA, TNF DPYD 32/4885GAA 33/4885ATAD2 2198/4885
US-20030194741-A1 COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES ADAR, RNMT, ATIC DPYD 519/4885GAA 3190/4885ATAD2 2080/4885
US-20030054410-A1 Combinatorial protecting group strategy for multifunctional molecules ADAR, RNMT, RRM1 DPYD 362/4885GAA 2513/4885ATAD2 1865/4885
US-20260146249-A1 ANTISENSE OLIGONUCLEOTIDES FOR TREATING A DISEASE OR CONDITION ASSOCIATED WITH AN ABNORMAL PROCESSING OF APP APP, PSEN2, PSEN1 DPYD 2591/4885GAA 220/4885ATAD2 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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