SCHEMBL28633959

SCHEMBL28633959

COc1ccc2c(OC)csc2c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.49
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
ALDH1A1 P00352 4/20 0.46
CYP3A4 P08684 2/20 0.46
MAPT P10636 2/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP1A1 P04798 3/20 0.42
CYP1B1 Q16678 3/20 0.42
TUBB4A P04350 2/20 0.42
TUBB P07437 2/20 0.42
TUBA3C P0DPH7 2/20 0.42
TUBA1B P68363 2/20 0.42
TUBA4A P68366 2/20 0.42
TUBB4B P68371 2/20 0.42
TUBB3 Q13509 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15953126 0.82 ESR1 (0.54) ESR1CA12CA1CA2CA7
SCHEMBL4797361 0.81 ALDH1A1 (0.44) ESR1ALDH1A1CYP3A4MAPTHSD17B10
SCHEMBL5544081 0.81 ALDH1A1 (0.44) ESR1CA12CA1CA2CA7
SCHEMBL34459993 0.81 ALDH1A1 (0.44) ESR1CA12CA1CA2CA7
SCHEMBL5542992 0.79 ALDH1A1 (0.42) ESR1CA12CA1CA2CA7
SCHEMBL29768596 0.79 TSHR (0.46) ESR1ALDH1A1CYP3A4MAPTHSD17B10
SCHEMBL8056400 0.79 ALDH1A1 (0.48) ESR1CA2ALDH1A1CYP3A4MAPT
SCHEMBL28462880 0.79 ALDH1A1 (0.68) ESR1CA2ALDH1A1CYP3A4MAPT
SCHEMBL14599487 0.79 ALDH1A1 (0.42) ESR1CA12CA1CA2CA7
SCHEMBL5815037 0.77 MAOB (0.44) ALDH1A1MAPTHSD17B10CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109233799-B Red electrochromic polymer material, preparation method and application 北京大学深圳研究生院 2021-07-23 CN disclosed