Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34459993 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL28633959 | 0.79 | ESR1 (0.49) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL5544081 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL4797361 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL29768596 | 0.78 | TSHR (0.46) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL8056400 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL28462880 | 0.78 | ALDH1A1 (0.68) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL5542992 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MAPTHSD17B10ESR1TSHR | |
| SCHEMBL5815037 | 0.75 | MAOB (0.44) | ALDH1A1MAPTHSD17B10NPSR1TUBB4A | |
| SCHEMBL4796572 | 0.74 | CYP2A6 (0.51) | ALDH1A1MAPTHSD17B10ESR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021492-A1 | e.g. sulfamic acid, 1,2,3,4-tetrahydro-dibenzothiophene-7-yl-1,1-dioxide ester; estrogen-dependent diseases | LABORATOIRE THERAMEX (MC) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021492-A1 | e.g. sulfamic acid, 1,2,3,4-tetrahydro-dibenzothiophene-7-yl-1,1-dioxide ester; estrogen-dependent diseases | SULT1E1, SULT1A1, SULT2A1 | ALDH1A1 76/4885MAPT 1970/4885HSD17B10 340/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.