SCHEMBL28634004

SCHEMBL28634004

O=[PH]1Oc2ccccc2-c2cc(F)ccc21

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 4/20 0.33
PTPN1 P18031 1/20 0.33
STK17B O94768 1/20 0.33
GPR3 P46089 1/20 0.33
MAOB P27338 4/20 0.32
PDK2 Q15119 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
FABP6 P51161 1/20 0.30
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30781 0.80 HSP90AA1 (0.35)
SCHEMBL29395467 0.80 HSP90AA1 (0.35)
SCHEMBL29363087 0.80 HSP90AA1 (0.35)
Bromide SCHEMBL28619414 0.78 HSP90AA1 (0.34)
SCHEMBL6444080 0.78 HSP90AA1 (0.34)
Phosphine SCHEMBL28051578 0.78 HSP90AA1 (0.34)
SCHEMBL30598814 0.78 HSP90AA1 (0.34)
SCHEMBL31183036 0.78 HSP90AA1 (0.34)
SCHEMBL28437933 0.78 HSP90AA1 (0.34)
Alcohol SCHEMBL28762611 0.75 ALDH1A1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113337923-B Core-shell type low-dielectric-resistance flame-retardant polyimide-based fiber material and preparation method thereof 东南大学 2022-03-08 CN claimed
CN-113337923-A Core-shell type low-dielectric-resistance flame-retardant polyimide-based fiber material and preparation method thereof 东南大学 2021-09-03 CN claimed
CN-113337923-B Core-shell type low-dielectric-resistance flame-retardant polyimide-based fiber material and preparation method thereof 东南大学 2022-03-08 CN disclosed
CN-113337923-A Core-shell type low-dielectric-resistance flame-retardant polyimide-based fiber material and preparation method thereof 东南大学 2021-09-03 CN disclosed