Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.34 |
| ▸ | CDK9 | P50750 | 3/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20576173 | 1.00 | AXL (0.48) | AXLMAPK1ADORA2AADORA1CCNT1 | |
| SCHEMBL28634050 | 0.79 | AXL (0.52) | AXLMAPK1ADORA2AADORA1CCNT1 | |
| SCHEMBL21273862 | 0.76 | AXL (0.48) | AXLMAPK1ADORA2AADORA1CCNT1 | |
| SCHEMBL14635390 | 0.76 | ADORA2A (0.50) | AXLADORA2AADORA1 | |
| SCHEMBL29605205 | 0.76 | ADORA2A (0.50) | AXLADORA2AADORA1 | |
| Hydrochloric Acid SCHEMBL22717554 | 0.74 | GSK3B (0.37) | ADORA2AADORA1CCNT1CDK9CDK2 | |
| SCHEMBL21178475 | 0.72 | AXL (0.44) | AXLMAPK1CCNT1CDK9PIM1 | |
| SCHEMBL30204138 | 0.72 | AXL (0.44) | AXLMAPK1CCNT1CDK9PIM1 | |
| Hydrochloric Acid SCHEMBL21546039 | 0.68 | HTR2A (0.50) | — | |
| SCHEMBL30503527 | 0.68 | CDK5 (0.46) | AXLMAPK1ADORA2AADORA1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447954-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | Icahn School of Medicine at Mount Sinai (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |
| CN-108727369-B | Influenza virus replication inhibitors and uses thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |