SCHEMBL28634341

SCHEMBL28634341

Brc1ccc2nc3ccc(Br)cc3nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.58
PIK3R1 P27986 1/20 0.53
PIK3CA P42336 1/20 0.53
BACE1 P56817 2/20 0.50
HTT P42858 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.48
NQO2 P16083 5/20 0.46
MAPT P10636 3/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
CYP2A6 P11509 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL483060 1.00 PABPC1 (0.58) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL30179258 1.00 PABPC1 (0.58) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL16862275 0.92 NQO2 (0.57) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL30839234 0.92 NQO2 (0.57) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL30839235 0.92 NQO2 (0.57) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL28198392 0.89 PABPC1 (0.54) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL15196675 0.89 PABPC1 (0.54) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL24277660 0.86 NQO2 (0.65) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL10926535 0.85 PABPC1 (0.50) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL4143144 0.85 PABPC1 (0.55) PABPC1PIK3R1PIK3CABACE1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118812594-A Self-assembled phosphonic acid molecule with double functions, and preparation and application thereof 华中科技大学 2024-10-22 CN claimed
CN-118812594-A Self-assembled phosphonic acid molecule with double functions, and preparation and application thereof 华中科技大学 2024-10-22 CN disclosed
CN-106554322-B Phenazine derivative and application thereof in organic electroluminescent device 北京鼎材科技有限公司 2021-05-04 CN disclosed