SCHEMBL483060

SCHEMBL483060

Brc1ccc2nc3cc(Br)ccc3nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.58
PIK3R1 P27986 1/20 0.53
PIK3CA P42336 1/20 0.53
BACE1 P56817 2/20 0.50
HTT P42858 2/20 0.48
CYP2C19 P33261 2/20 0.48
CYP1A2 P05177 1/20 0.48
NQO2 P16083 5/20 0.46
MAPT P10636 3/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
CYP2A6 P11509 1/20 0.42
ALDH1A1 P00352 1/20 0.41
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30179258 1.00 PABPC1 (0.58) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL28634341 1.00 PABPC1 (0.58) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL16862275 0.92 NQO2 (0.57) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL30839234 0.92 NQO2 (0.57) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL30839235 0.92 NQO2 (0.57) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL28198392 0.89 PABPC1 (0.54) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL15196675 0.89 PABPC1 (0.54) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL24277660 0.86 NQO2 (0.65) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL10926535 0.85 PABPC1 (0.50) PABPC1PIK3R1PIK3CABACE1HTT
SCHEMBL4143144 0.85 PABPC1 (0.55) PABPC1PIK3R1PIK3CABACE1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3696602-B1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING DEVICE, AND WINDOW MATERIAL CANON KK (JP) 2025-06-11 EP disclosed
EP-3696603-B1 ELECTROCHROMIC ELEMENT, OPTICAL FILTER, LENS UNIT, IMAGING DEVICE, AND WINDOW MATERIAL CANON KK (JP) 2025-06-04 EP disclosed
US-12174404-B2 Light-controlling device CANON KABUSHIKI KAISHA (JP) 2024-12-24 US disclosed
US-12081855-B2 Light modulating element and optical apparatus, imaging apparatus and lens unit using the same CANON KABUSHIKI KAISHA (JP) 2024-09-03 US disclosed
US-12078905-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2024-09-03 US disclosed
CN-117820345-A Blue light material based on dibenzofuran-aza condensed ring, preparation and application thereof 山西大同大学 2024-04-05 CN disclosed
US-11661546-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2023-05-30 US disclosed
US-11661546-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2023-05-30 US disclosed
US-11661546-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member CANON KABUSHIKI KAISHA (JP) 2023-05-30 US disclosed
CN-113196114-B Light control element 佳能株式会社 2023-02-28 CN disclosed
US-20120040962-A1 FUSED RING INHIBITORS OF HEPATITIS C PRESIDIO PHARMACEUTICALS, INC. (US) 2012-02-16 US disclosed
US-20120040962-A1 FUSED RING INHIBITORS OF HEPATITIS C PRESIDIO PHARMACEUTICALS, INC. (US) 2012-02-16 US disclosed
US-20120040962-A1 FUSED RING INHIBITORS OF HEPATITIS C PRESIDIO PHARMACEUTICALS, INC. (US) 2012-02-16 US disclosed
EP-2410843-A1 FUSED RING INHIBITORS OF HEPATITIS C Presidio Pharmaceuticals, Inc. (US) 2012-02-01 EP disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
US-8101776-B2 Organic semiconductors and their manufacture BASF SE (DE) 2012-01-24 US disclosed
WO-2010111534-A1 FUSED RING INHIBITORS OF HEPATITIS C PRESIDIO PHARMACEUTICALS, INC. (US) 2010-09-30 WO disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
US-20090299070-A1 Organic Semiconductors and Their Manufacture CLAP CO., LTD. (KR) 2009-12-03 US disclosed
WO-2007068618-A1 ORGANIC SEMICONDUCTORS AND THEIR MANUFACTURE CIBA HOLDING INC. (CH) 2007-06-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299070-A1 Organic Semiconductors and Their Manufacture YBX1, CDYL, PROX1 PABPC1 3437/4885PIK3R1 2953/4885PIK3CA 1484/4885
US-12078905-B2 Electrochromic element, optical filter, lens unit, image pickup apparatus, and window member HCN2, HCN4, HCN3 PABPC1 3229/4885PIK3R1 1221/4885PIK3CA 1102/4885
US-20120040962-A1 FUSED RING INHIBITORS OF HEPATITIS C HAVCR2, HCCS, ZC3HAV1 PABPC1 937/4885PIK3R1 330/4885PIK3CA 927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.