Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 14/20 | 0.48 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634457 | 1.00 | TRPV3 (0.48) | TRPV3PDCD1LG2CD274ALDH1A1CYP1A2 | |
| SCHEMBL22345810 | 0.88 | TRPV3 (0.44) | TRPV3 | |
| SCHEMBL30850043 | 0.88 | TRPV3 (0.44) | TRPV3 | |
| SCHEMBL20268380 | 0.87 | TRPV3 (0.42) | TRPV3PDCD1LG2CD274 | |
| SCHEMBL22345797 | 0.87 | TRPV3 (0.42) | TRPV3PDCD1LG2CD274 | |
| SCHEMBL29442719 | 0.87 | TRPV3 (0.42) | TRPV3PDCD1LG2CD274 | |
| SCHEMBL20268384 | 0.87 | TRPV3 (0.42) | TRPV3PDCD1LG2CD274 | |
| SCHEMBL30850026 | 0.87 | TRPV3 (0.42) | TRPV3PDCD1LG2CD274 | |
| SCHEMBL22345802 | 0.83 | TRPV3 (0.49) | TRPV3PDCD1LG2CD274ALDH1A1CYP1A2 | |
| SCHEMBL22345799 | 0.83 | TRPV3 (0.49) | TRPV3PDCD1LG2CD274ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206566-A | Hydroxypyridooxazepine as NRF2 activator | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113474349-B | Hydroxypyridooxazepine as NRF2 activator | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-113474349-A | Hydroxypyridooxazepine heptatrienes as NRF2 activators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-01 | — | — | CN | disclosed |