Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634475 | 0.89 | ABCB1 (0.38) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL28634476 | 0.89 | ABCB1 (0.38) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL24140420 | 0.82 | ABCB1 (0.62) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL30360077 | 0.81 | ABCB1 (0.44) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL10042788 | 0.80 | RAB9A (0.52) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL28629445 | 0.80 | ABCB1 (0.43) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL28629446 | 0.80 | ABCB1 (0.43) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL20529546 | 0.79 | RAB9A (0.54) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL20529544 | 0.79 | RAB9A (0.54) | ABCB1RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL24140270 | 0.78 | ABCB1 (0.37) | ABCB1RAB9ANPC1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4171653-A2 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | Regeneron Pharmaceuticals, Inc. (US) | 2023-05-03 | — | — | EP | disclosed |
| US-20230069722-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. | 2023-03-02 | — | — | US | disclosed |
| WO-2021262910-A2 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | REGENERON PHARMACEUTICALS, INC. (US) | 2021-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230069722-A1 | TUBULYSINS AND PROTEIN-TUBULYSIN CONJUGATES | SDCBP, TEK, TEKT1 | ABCB1 895/4885RAB9A 1892/4885NPC1 2301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.