SCHEMBL28634577

SCHEMBL28634577

CONC(=O)C(C)(C)Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8255036 0.78
SCHEMBL21126154 0.76
SCHEMBL19407344 0.76
SCHEMBL15341473 0.73 ALOX15 (0.32)
SCHEMBL19407346 0.72
SCHEMBL29434928 0.70
SCHEMBL4386907 0.70
Hydrochloric Acid SCHEMBL31646876 0.70
SCHEMBL12385190 0.70 RIPK1 (0.40)
SCHEMBL654171 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429424-B Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative 华侨大学 2022-06-07 CN claimed
CN-113429424-A Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative 华侨大学 2021-09-24 CN claimed
CN-122010865-A 1,4, 11-Trioxo-10, 14-diazaspirocyclic sunflower ketone and synthesis method and application thereof 广西师范大学 2026-05-12 CN disclosed
CN-117946025-A 1-Oxygen-2, 8-diazacyclic sunflower ketone derivative and synthetic method and application thereof 广西师范大学 2024-04-30 CN disclosed
CN-113429424-B Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative 华侨大学 2022-06-07 CN disclosed
CN-113429424-A Preparation method of [1,2,4] oxadiazino indoline-3-ketone derivative 华侨大学 2021-09-24 CN disclosed