Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PYGL | P06737 | 4/20 | 0.57 |
| ▸ | PYGM | P11217 | 4/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.51 |
| ▸ | GALK1 | P51570 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | PLEC | Q15149 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637726 | 0.88 | POLB (0.67) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL29393214 | 0.88 | POLB (0.67) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL140780 | 0.88 | POLB (0.67) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL523225 | 0.84 | POLB (0.63) | POLBPYGLPYGMHPSEXDH | |
| SCHEMBL522949 | 0.84 | POLB (0.77) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL30287662 | 0.84 | POLB (0.77) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL29364655 | 0.84 | POLB (0.70) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL29426403 | 0.84 | POLB (0.70) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL49365 | 0.84 | POLB (0.70) | POLBPYGLPYGMHPSETDP1 | |
| SCHEMBL28576596 | 0.82 | POLB (0.75) | POLBPYGLPYGMHPSETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292494-A | Isoquinoline carboxylic acid compound and preparation method and application thereof | 江苏苏中药业集团股份有限公司 | 2021-08-24 | — | — | CN | disclosed |