SCHEMBL28634816

SCHEMBL28634816

Clc1cccc(Cl)c1-c1c[nH]c(-c2cnccn2)n1

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.42
JAK2 O60674 2/20 0.41
NPY5R Q15761 2/20 0.41
PIEZO1 Q92508 4/20 0.37
GRK6 P43250 1/20 0.36
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 2/20 0.35
PIM2 Q9P1W9 1/20 0.35
ADORA2A P29274 1/20 0.34
PKM P14618 1/20 0.34
P2RX7 Q99572 2/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29712839 1.00 METAP2 (0.42) METAP2JAK2NPY5RPIEZO1GRK6
SCHEMBL29712840 0.85 P2RX7 (0.42) METAP2NPY5RPIEZO1GRK6NPC1
SCHEMBL28627684 0.85 P2RX7 (0.42) METAP2NPY5RPIEZO1GRK6NPC1
SCHEMBL28406387 0.82 CBFB (0.47) METAP2NPY5RHPGDHSD17B10NPC1
SCHEMBL17280232 0.80 GRK6 (0.48) METAP2NPY5RGRK6PIM2
SCHEMBL28402334 0.79 NPY5R (0.45) JAK2NPY5RALDH1A1SMN1; SMN2
SCHEMBL28629827 0.78 NPY5R (0.63) METAP2NPY5RHPGDNPC1RAB9A
SCHEMBL29712850 0.78 NPY5R (0.63) METAP2NPY5RHPGDNPC1RAB9A
SCHEMBL7143203 0.78 NPC1 (0.50) METAP2NPY5RHPGDNPC1RAB9A
SCHEMBL29712872 0.78 NPY5R (0.42) METAP2NPY5RGRK6NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113234062-B Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent 赣州市贝加尔电子材料有限公司 2022-07-08 CN claimed
CN-113234062-A Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent 赣州市贝加尔电子材料有限公司 2021-08-10 CN claimed
CN-113234062-B Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent 赣州市贝加尔电子材料有限公司 2022-07-08 CN disclosed
CN-113234062-A Pyrazinylimidazole compound, weldable protective agent, preparation method and application of pyrazinylimidazole compound and weldable protective agent 赣州市贝加尔电子材料有限公司 2021-08-10 CN disclosed