Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25424391 | 0.86 | TSHR (0.54) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL3915386 | 0.86 | TSHR (0.63) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL6929436 | 0.84 | TSHR (0.51) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL11062033 | 0.82 | TSHR (0.54) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL751504 | 0.82 | TSHR (0.54) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL194452 | 0.81 | ALDH1A1 (0.56) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL1405431 | 0.81 | ALDH1A1 (0.49) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL2531577 | 0.81 | TSHR (0.56) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL8982565 | 0.81 | TSHR (0.43) | TSHRALDH1A1CYP3A4CA2PRSS1 | |
| SCHEMBL3268991 | 0.80 | TSHR (0.51) | TSHRALDH1A1CYP3A4CA2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108780166-B | Composition for high-refractive-index low-dispersion resin for composite diffractive optical element, and composite diffractive optical element using same | 三菱瓦斯化学株式会社 | 2021-09-28 | — | — | CN | disclosed |