SCHEMBL2863486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27536113	0.85	MAP2K4 (0.47)	MAP2K4TTKKDRGSK3AGSK3B
	SCHEMBL2864633	0.84	MAP2K4 (0.47)	MAP2K4DHODHMAPK1MAPK6DCLRE1B
	SCHEMBL2857443	0.82	CA12 (0.46)	MAP2K4DHODHMAPK1MAPK6MAPKAPK3
	SCHEMBL2866826	0.82	DYRK1A (0.52)	MAP2K4KDRGSK3AGSK3B
	SCHEMBL4334940	0.80	MAP4K4 (0.48)	MAP2K4MAPK1TTKNOTUMGSK3B
	SCHEMBL4338787	0.79	MAP2K4 (0.40)	MAP2K4MAPK1TTKKDR
	SCHEMBL4343387	0.79	MAPK1 (0.52)	MAPK1
	SCHEMBL2861737	0.79	MAP2K4 (0.43)	MAP2K4TTKNOTUMKDRHTR7
	SCHEMBL4340944	0.79	DYRK1A (0.38)	MAP2K4MAPK1KDRGRK6GSK3B
	SCHEMBL4340999	0.79	WNT1 (0.51)	MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.