SCHEMBL4340944

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4334940	0.88	MAP4K4 (0.48)	DYRK1AMAP2K4CDK4CCND1NTRK1
	SCHEMBL4340999	0.86	WNT1 (0.51)	DYRK1AWNT1MAPK1
	SCHEMBL4339198	0.85	MAPK1 (0.47)	DYRK1AMAP2K4CDK4CCND1NTRK1
	SCHEMBL4336321	0.83	MAPK1 (0.43)	DYRK1AMAP2K4CDK4CCND1NTRK1
	SCHEMBL4346817	0.81	TAAR1 (0.49)	CDK4CCND1MAPK1
	SCHEMBL4331947	0.80	NAMPT (0.45)	CDK4CCND1JAK2JAK3TP53
	SCHEMBL2866826	0.80	DYRK1A (0.52)	DYRK1AMAP2K4GSK3BWNT1MAP4K4
	SCHEMBL27536113	0.79	MAP2K4 (0.47)	DYRK1AMAP2K4NTRK1GSK3BJAK2
	SCHEMBL4341000	0.79	NPC1 (0.51)	—
	SCHEMBL2864882	0.79	TP53 (0.53)	TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.