SCHEMBL28634860

SCHEMBL28634860

CSCC[C@@H]([C]=O)NC(=O)c1cccc(CN)c1

nearest known ligand 0.48

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FNTA P49354 13/20 0.48
FNTB P49356 13/20 0.48
PGGT1B P53609 3/20 0.48
LOXL2 Q9Y4K0 1/20 0.46
F10 P00742 2/20 0.41
PRSS1 P07477 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064439 0.82 FNTA (0.67) FNTAFNTBPGGT1B
SCHEMBL28630859 0.81 FNTA (0.49) FNTAFNTBPGGT1B
SCHEMBL8369448 0.80 FNTA (0.68) FNTAFNTBPGGT1BLOXL2
SCHEMBL8369449 0.80 FNTA (0.68) FNTAFNTBPGGT1BLOXL2
SCHEMBL22970168 0.71 HDAC1 (0.49) FNTAFNTBPGGT1B
SCHEMBL21241960 0.71 HDAC1 (0.49) FNTAFNTBPGGT1B
SCHEMBL14602466 0.71 LOXL2 (0.55) LOXL2F10PRSS1
SCHEMBL15601947 0.71 FNTA (0.66) FNTAFNTBPGGT1B
SCHEMBL27516944 0.70 HPGDS (0.50) LOXL2F10PRSS1
SCHEMBL6388386 0.70 LOXL2 (0.65) LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113301920-A Complexes comprising ligands, spacers, peptide linkers and biomolecules 安斯泰来制药株式会社 2021-08-24 CN disclosed
CN-113271973-A Complex comprising a ligand and a CEACAM5 antibody Fab fragment 安斯泰来制药株式会社 2021-08-17 CN disclosed