Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634991 | 1.00 | ALOX15 (0.39) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL16878867 | 0.83 | ALOX15 (0.39) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL28017570 | 0.83 | ALOX15 (0.39) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL16873913 | 0.77 | ALOX15 (0.34) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL28637134 | 0.75 | APLNR (0.33) | LMNASMN1; SMN2TSHR | |
| SCHEMBL13367959 | 0.73 | — | — | |
| SCHEMBL8131724 | 0.72 | — | — | |
| SCHEMBL27168474 | 0.72 | ALOX15 (0.37) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL3689246 | 0.72 | CYP1A2 (0.32) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL30211246 | 0.71 | CETP (0.44) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641906-B | Heteroaryl substituted aminopyridine compounds | 百时美施贵宝公司 | 2021-10-01 | — | — | CN | disclosed |