SCHEMBL28635284

SCHEMBL28635284

Cc1ccc(Br)c(C2CC(=O)C2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
MAP1LC3B Q9GZQ8 1/20 0.36
ACHE P22303 1/20 0.36
BRD4 O60885 1/20 0.36
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
AADAT Q8N5Z0 2/20 0.34
SRD5A1 P18405 2/20 0.33
TP53 P04637 1/20 0.33
RECQL P46063 1/20 0.33
ELANE P08246 1/20 0.33
GRM7 Q14831 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ALDH2 P05091 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30558904 0.93 TP53 (0.42) CHRNB2CHRNA4MAP1LC3BACHEBRD4
SCHEMBL25376332 0.81 TP53 (0.34) HTR2AHTR2CHTR2BTP53RECQL
SCHEMBL16962649 0.80 CHRNB2 (0.41) CHRNB2CHRNA4HTR2AHTR2CHTR2B
SCHEMBL25374451 0.79 TP53 (0.33) TP53RECQLGRM7
SCHEMBL3409002 0.77 PTGDR2 (0.45) CHRNB2CHRNA4HTR2AHTR2CHTR2B
SCHEMBL25554158 0.77 GRM7 (0.49) CHRNB2CHRNA4ACHEBRD4AADAT
SCHEMBL23625888 0.74 TP53 (0.49) CHRNB2CHRNA4MAP1LC3BACHEAADAT
SCHEMBL7560192 0.74 TP53 (0.44) CHRNB2CHRNA4ACHETP53RECQL
SCHEMBL27278200 0.73 CHRNB2 (0.36) CHRNB2CHRNA4HTR2AHTR2CHTR2B
SCHEMBL28571106 0.72 BRD4 (0.56) MAP1LC3BBRD4HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214067-B Preparation method of indanone compound 长春工业大学 2023-06-30 CN disclosed
CN-113214067-A Preparation method of indanone compounds 长春工业大学 2021-08-06 CN disclosed