SCHEMBL3409002

SCHEMBL3409002

Cc1ccc(Br)c(C2CCCC2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 2/20 0.45
RAB9A P51151 4/20 0.39
NPC1 O15118 3/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
NOS3 P29474 2/20 0.37
NOS1 P29475 2/20 0.37
NOS2 P35228 2/20 0.37
HTR2A P28223 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
PSMB5 P28074 2/20 0.36
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
PTGDR Q13258 1/20 0.33
CASP3 P42574 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16962649 0.92 CHRNB2 (0.41) PTGDR2RAB9ANPC1CHRNB2CHRNA4
SCHEMBL19308494 0.79 PTGDR2 (0.47) PTGDR2RAB9ANPC1CHRNB2CHRNA4
SCHEMBL7422191 0.78 PTGDR2 (0.50) PTGDR2RAB9ANPC1CHRNB2CHRNA4
SCHEMBL28899720 0.78 PTGDR (0.50) PTGDR2RAB9ANPC1NOS3NOS1
SCHEMBL28635284 0.77 CHRNB2 (0.37) RAB9ANPC1CHRNB2CHRNA4HTR2A
SCHEMBL10206355 0.76 PTGDR2 (0.45) PTGDR2RAB9ANPC1CHRNB2CHRNA4
SCHEMBL11421553 0.76 TDP1 (0.46) PTGDR2RAB9ANPC1CHRNB2CHRNA4
SCHEMBL7718403 0.76 NUDT1 (0.51) PTGDR2RAB9ANPC1CHRNB2CHRNA4
P-Xylene SCHEMBL9420802 0.76 PTGDR2 (0.49) PTGDR2RAB9ANPC1CHRNB2CHRNA4
SCHEMBL17026778 0.76 PTGDR2 (0.46) PTGDR2CHRNB2CHRNA4NOS3NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2260032-A2 FUNGICIDAL HETERCYCLIC COMPOUNDS E. I. du Pont de Nemours and Company (US) 2010-12-15 EP disclosed
WO-2009094445-A2 FUNGICIDAL HETERCYCLIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-30 WO disclosed