SCHEMBL28635446

SCHEMBL28635446

COOC(C)(C)C(=O)OOC(=O)C(C)(C)OOC

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.37
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28824596 0.80 TSHR (0.47) DGAT1ALDH1A1TSHRTDP1HSD17B10
SCHEMBL27565157 0.72 DGAT1 (0.37) DGAT1ALDH1A1
SCHEMBL28944483 0.70 DGAT1 (0.46) DGAT1ALDH1A1TSHRTDP1HSD17B10
SCHEMBL758634 0.69 DGAT1 (0.50) DGAT1ALDH1A1TSHRTDP1
SCHEMBL13481936 0.67 TSHR (0.35) TSHRTDP1
SCHEMBL1141547 0.65 ELANE (0.40) DGAT1ALDH1A1TSHR
SCHEMBL10613510 0.65 TSHR (0.39) DGAT1ALDH1A1TSHRTDP1HSD17B10
SCHEMBL10832754 0.65 DGAT1 (0.41) DGAT1ALDH1A1
SCHEMBL5739290 0.65 DGAT1 (0.46) DGAT1ALDH1A1
SCHEMBL28343431 0.65 ALDH1A1 (0.35) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113402647-A Regulating and controlling method and synthesizing method for synthesizing EVA (ethylene vinyl acetate copolymer) with controllable release of free radicals, EVOH (ethylene vinyl alcohol) resin and synthesizing method thereof 中国科学院长春应用化学研究所 2021-09-17 CN disclosed