Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.77 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PER2 | O15055 | 3/20 | 0.46 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.46 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.46 |
| ▸ | TSPO | P30536 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30897307 | 1.00 | DNM1 (0.77) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29391692 | 0.88 | DNM1 (1.00) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL410147 | 0.88 | DNM1 (1.00) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL29351340 | 0.88 | DNM1 (1.00) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL28641677 | 0.88 | TSPO (0.64) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL30897308 | 0.88 | TSPO (0.64) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20334192 | 0.82 | DNM1 (0.88) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL14689975 | 0.81 | DNM1 (0.80) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL410692 | 0.81 | DNM1 (0.85) | DNM1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL406986 | 0.79 | DNM1 (0.78) | DNM1MAPTKMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402444-B | Carbazole compound and application thereof in preparation of medicines for treating fatty liver and type 2 diabetes and other metabolic related diseases | 上海欧坤生物医药科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-113402444-A | Carbazole compound and application thereof in preparation of medicines for treating metabolic related diseases such as fatty liver and type 2 diabetes | 上海欧坤生物医药科技有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-113402444-B | Carbazole compound and application thereof in preparation of medicines for treating fatty liver and type 2 diabetes and other metabolic related diseases | 上海欧坤生物医药科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-113402444-A | Carbazole compound and application thereof in preparation of medicines for treating metabolic related diseases such as fatty liver and type 2 diabetes | 上海欧坤生物医药科技有限公司 | 2021-09-17 | — | — | CN | disclosed |