SCHEMBL286359

SCHEMBL286359

Cc1cccc(Br)c1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30978689 1.00
SCHEMBL416374 0.80
SCHEMBL16776729 0.80 CD44 (0.72)
SCHEMBL106244 0.80
SCHEMBL4537402 0.78 ALDH1A1 (0.60)
SCHEMBL6687694 0.77 CD44 (0.68)
Bromide SCHEMBL10391086 0.77 CD44 (0.68)
Bromide SCHEMBL28506748 0.77 CD44 (0.68)
SCHEMBL30355145 0.77 CD44 (0.68)
Ammonia Solution, Strong SCHEMBL1289383 0.77 CD44 (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-107652276-A A kind of preparation method net SGLT2 inhibitor Yi Palie 江苏工程职业技术学院 2018-02-02 CN claimed
CN-104844514-B Diaryl pyrazole azole compound and preparation method and application 山东大学 2017-11-10 CN claimed
CN-104478670-B The preparation method of the bromo-2-of 5-chloro-4 '-ethoxy diphenyl methane 中国药科大学 2016-08-17 CN claimed
EP-2417125-B1 N-ARYL-2-(2-ARYLAMINOPYRIMIDIN-4-YL)PYRROL-4-CARBOXAMIDE DERIVATIVES AS MPS1 KINASE INHIBITORS NERVIANO MEDICAL SCIENCES SRL (IT) 2015-09-09 EP claimed
CN-104844514-A Diarylpyrazole compound as well as preparation method and application thereof UNIV SHANDONG 2015-08-19 CN claimed
CN-104478670-A Preparation method of 5-bromine-2-chlorine-4'-ethyoxyl diphenylmethane UNIV CHINA PHARMA 2015-04-01 CN claimed
CN-103041855-B Preparation method of catalysts for dichloro-pyridine oxynitride SHANGHAI NOVEL CHEMICAL TECHNOLOGY CO LTD 2014-09-10 CN claimed
US-8772280-B2 N-aryl-2-(2-arylaminopyrimidin-4-yl)pyrrol-4-carboxamide derivatives as MPS1 kinase inhibitors NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2014-07-08 US claimed
EP-1903030-B1 Method for catalytic manufacture of aromatic or heteroaromatic nitriles SALTIGO GMBH (DE) 2014-06-04 EP claimed
CN-103787895-A Production process for synthesizing 4-bromo-2-methylaniline ANHUI HUARUN PAINTS CO LTD 2014-05-14 CN claimed
WO-2010108921-A1 N-ARYL-2-(2-ARYLAMINOPYRIMIDIN-4-YL)PYRROL-4-CARBOXAMIDE DERIVATIVES AS MPS1 KINASE INHIBITORS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2010-09-30 WO claimed
US-7592452-B2 Process for catalytically preparing aromatic or heteroaromatic nitriles SALTIGOGMBH (DE) 2009-09-22 US claimed
US-20090062541-A1 Process for catalytically preparing aromatic or heteroaromatic nitriles SALTIGO GMBH (DE) 2009-03-05 US claimed
EP-1903030-A1 Method for catalytic manufacture of aromatic or heteroaromatic nitriles Saltigo GmbH (DE) 2008-03-26 EP claimed
CN-1946675-A Separation of amine from a phenolic compound DU PONT (US) 2007-04-11 CN claimed
US-12617802-B2 Sulfonimidamide compounds as NLRP3 modulators GENENTECH, INC. (US) 2026-05-05 US disclosed
US-20250381187-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC. (US) 2025-12-18 US disclosed
US-3978040-A Process for the preparation of cyanoazo compounds by reacting halogenoazo compounds with CuCN in an aqueous media in the presence of a nitrogen base BAYER AKTIENGESELLSCHAFT (DT) 1976-08-31 US disclosed
US-3962209-A PROCESS FOR PREPARING AZO DYESTUFFS WITH ORTHO-AZO CYANO GROUPS BY CYANO EXCHANGE OF METAL CYANIDES AND HALO DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed