Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.63 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.63 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.51 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747456 | 1.00 | SIRT6 (0.63) | SIRT6SIRT1SLC6A5GNAI3GNAO1 | |
| SCHEMBL23835515 | 1.00 | SIRT6 (0.63) | SIRT6SIRT1SLC6A5GNAI3GNAO1 | |
| SCHEMBL8760408 | 0.96 | SIRT6 (0.57) | SIRT6SIRT1SLC6A5GNAI3GNAO1 | |
| SCHEMBL12216484 | 0.91 | EPHX1 (0.61) | FOLH1EPHX1SMN1; SMN2EPHX2NOD1 | |
| SCHEMBL20542964 | 0.89 | SIRT1 (0.80) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL20542962 | 0.89 | SIRT1 (0.80) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL20543122 | 0.89 | SIRT1 (0.80) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| SCHEMBL20543120 | 0.89 | SIRT1 (0.80) | SIRT6SIRT1GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL20543112 | 0.87 | SIRT1 (0.78) | SIRT6SIRT1SLC6A5GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL20543035 | 0.87 | SIRT1 (0.78) | SIRT6SIRT1SLC6A5GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820146-B2 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2010-10-26 | — | — | US | disclosed |
| EP-1515684-B1 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | OREAL (FR) | 2010-05-19 | — | — | EP | disclosed |
| US-20050245673-A1 | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | L'OREAL S.A. (FR) | 2005-11-03 | — | — | US | disclosed |
| CN-1658819-A | Care and/or make-up cosmetic composition structured with silicone polymers and organogelling agents, in rigid form | OREAL (FR) | 2005-08-24 | — | — | CN | disclosed |
| EP-1515684-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003105788-A2 | CARE AND/OR MAKE-UP COSMETIC COMPOSITION STRUCTURED WITH SILICONE POLYMERS AND ORGANOGELLING AGENTS, IN RIGID FORM | L'OREAL (FR) | 2003-12-24 | — | — | WO | disclosed |