SCHEMBL28636591 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	LMNA	P02545	1/20	0.41

▸	HRH4	Q9H3N8	4/20	0.38

▸	HRH3	Q9Y5N1	4/20	0.38

▸	DRD1	P21728	1/20	0.37

▸	TAAR1	Q96RJ0	1/20	0.36

▸	TSHR	P16473	1/20	0.35

▸	PTPN1	P18031	1/20	0.35

▸	CDC25B	P30305	1/20	0.35

▸	CTSL	P07711	1/20	0.34

▸	CTSB	P07858	1/20	0.34

▸	CTSK	P43235	1/20	0.34

▸	BUB1	O43683	1/20	0.34

▸	EPHX2	P34913	1/20	0.33

▸	PDE4D	Q08499	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28923047	0.90	LMNA (0.40)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28621831	0.87	LMNA (0.44)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28636592	0.85	LMNA (0.42)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28102974	0.80	LMNA (0.44)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL21753776	0.78	LMNA (0.42)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28802201	0.75	LMNA (0.47)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL524359	0.75	LMNA (0.47)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28802203	0.75	LMNA (0.47)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28397236	0.74	CTSL (0.42)	LMNAHRH4HRH3DRD1TAAR1
SCHEMBL28622017	0.73	LMNA (0.41)	LMNAHRH4HRH3PTPN1CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-113382994-A	Antiviral nucleosides and derivatives thereof	詹森生物制药有限公司	2021-09-10	—	—	CN	disclosed