Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032138 | 0.85 | KDM4E (0.39) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL21955361 | 0.79 | KDM4E (0.39) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL22032173 | 0.78 | KDM4E (0.38) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL38658847 | 0.76 | CA1 (0.42) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL4486453 | 0.73 | KDM4E (0.49) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL18397725 | 0.73 | SLC6A3 (0.40) | KMT2ASLC6A3KDM4ECA1CA2 | |
| SCHEMBL17873248 | 0.72 | CA1 (0.39) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL22084664 | 0.72 | KDM4E (0.37) | HTTKMT2ASLC6A3KDM4ESMN1; SMN2 | |
| SCHEMBL5723027 | 0.72 | KDM4E (0.55) | KMT2ASLC6A3KDM4ESMN1; SMN2CA1 | |
| SCHEMBL10320877 | 0.72 | KDM4E (0.48) | KDM4ESMN1; SMN2CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108341814-B | JAK kinase inhibitors and uses thereof | 上海翔锦生物科技有限公司 | 2021-09-03 | — | — | CN | disclosed |