SCHEMBL17873248

SCHEMBL17873248

COC(=O)c1ccc(Br)c2c1COC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
CA12 O43570 2/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
PDK2 Q15119 1/20 0.39
PDK4 Q16654 1/20 0.39
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.37
TSHR P16473 1/20 0.37
KDM4E B2RXH2 6/20 0.37
ALDH1A1 P00352 5/20 0.37
GAA P10253 4/20 0.37
GLA P06280 3/20 0.37
HSD17B10 Q99714 3/20 0.37
HPGD P15428 2/20 0.37
ATM Q13315 2/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18397725 0.81 SLC6A3 (0.40) CA1CA2CA9CA12CA7
SCHEMBL38658847 0.81 CA1 (0.42) CA1CA2CA9CA12CA7
SCHEMBL17873234 0.80 KDM4E (0.47) CA1CA2CA9CA12CA7
SCHEMBL22032149 0.76 KDM4E (0.37) CA1CA2CA9CA12CA7
SCHEMBL22084664 0.76 KDM4E (0.37) CA1CA2CA9CA12CA7
SCHEMBL22032138 0.74 KDM4E (0.39) CA1CA2CA9CA12CA7
SCHEMBL22032173 0.73 KDM4E (0.38) CA1CA2CA9CA12CA7
SCHEMBL21955179 0.73 CYP2A13 (0.34)
SCHEMBL30915590 0.73 CYP2A13 (0.34)
SCHEMBL18397692 0.72 DRD2 (0.38) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663626-A1 IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF Bio Genuine (Shanghai) Biotech Co., Ltd (CN) 2025-12-17 EP disclosed
CN-119874674-A GLP-1R modulating compounds 吉利德科学公司 2025-04-25 CN disclosed
CN-114630823-B GLP-1R Modulating Compounds 吉利德科学公司 2025-01-28 CN disclosed
WO-2024165071-A1 IMINE COMPOUNDS AS WELL AS PREPARATION METHOD THEREFOR AND USE THEREOF 上海葆正医药科技有限公司 2024-08-15 WO disclosed
US-11702404-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2023-07-18 US disclosed
US-11702404-B2 GLP-1R modulating compounds GILEAD SCIENCES, INC. (US) 2023-07-18 US disclosed
EP-4048664-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2022-08-31 EP disclosed
CN-114630823-A GLP-1R modulating compounds 吉利德科学公司 2022-06-14 CN disclosed
WO-2021081207-A1 GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES, INC. (US) 2021-04-29 WO disclosed
CN-107108596-B Oxazoline compounds substituted by fused ring systems 巴斯夫欧洲公司 2021-01-12 CN disclosed
EP-3237410-A1 AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM BASF SE (DE) 2017-11-01 EP disclosed
WO-2016102482-A1 AZOLINE COMPOUNDS SUBSTITUTED BY A CONDENSED RING SYSTEM BASF SE (DE) 2016-06-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11702404-B2 GLP-1R modulating compounds GLP1R, GIPR, GPR119 CA1 4287/4885CA2 3698/4885CA9 3902/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.