Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.52 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14708808 | 0.92 | CHKA (0.52) | CHKACDK1LMNACHRM2CHRM4 | |
| SCHEMBL6388962 | 0.85 | CHKA (0.57) | CHKACDK1LMNACHRM2CHRM4 | |
| SCHEMBL11139089 | 0.82 | CHKA (0.53) | CHKACDK1LMNACHRM2CHRM4 | |
| SCHEMBL14708807 | 0.82 | FERMT2 (0.61) | CDK1LMNACHRM2CHRM4CHRM5 | |
| SCHEMBL3229048 | 0.76 | CDK1 (0.66) | CHKACDK1LMNACHRM2CHRM4 | |
| SCHEMBL30058586 | 0.76 | CHKA (0.68) | CHKALMNANR4A2SOS2FERMT2 | |
| SCHEMBL1706258 | 0.76 | CHKA (0.68) | CHKALMNANR4A2SOS2FERMT2 | |
| SCHEMBL15475876 | 0.75 | CHKA (0.58) | CHKALMNACHRM2CHRM4CHRM5 | |
| SCHEMBL1147338 | 0.74 | NR4A2 (0.55) | CHKACDK1LMNACHRM2CHRM4 | |
| SCHEMBL13739086 | 0.74 | FERMT2 (0.69) | CDK1LMNANR4A2FERMT2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512001-A | Preparation method of hydroxychloroquine | 浙江苏泊尔制药有限公司 | 2021-10-19 | — | — | CN | disclosed |