Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.68 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10081937 | 0.94 | KMT2A (0.58) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL28639437 | 0.82 | PKM (0.51) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL1663469 | 0.81 | PARP10 (0.65) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL5050902 | 0.81 | PARP10 (0.65) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL754740 | 0.81 | PARP10 (1.00) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL6284986 | 0.78 | KMT2A (0.64) | PARP10KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5799799 | 0.78 | PARP10 (0.64) | PARP10KMT2AALDH1A1SMN1; SMN2PARP15 | |
| SCHEMBL14783590 | 0.77 | KMT2A (0.62) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL11903558 | 0.77 | KMT2A (0.44) | PARP10PARP3KMT2AALDH1A1KDM4E | |
| SCHEMBL31238525 | 0.77 | PARP10 (0.62) | PARP10PARP3KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |