Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12347521 | 0.83 | ALDH1A1 (0.44) | SMN1; SMN2LMNATP53ALDH1A1KDM4E | |
| SCHEMBL4611372 | 0.81 | KMT2A (0.53) | LMNATP53ALDH1A1TRPM8TSHR | |
| SCHEMBL15938456 | 0.81 | TSHR (0.55) | SMN1; SMN2LMNAALDH1A1KDM4ETRPM8 | |
| SCHEMBL3309083 | 0.80 | AKR1C3 (0.53) | SMN1; SMN2LMNAALDH1A1KDM4ETSHR | |
| SCHEMBL14164778 | 0.79 | MEN1 (0.57) | SMN1; SMN2LMNATP53ALDH1A1KDM4E | |
| SCHEMBL308205 | 0.79 | POLB (0.59) | TP53ALDH1A1TSHRKMT2APOLB | |
| SCHEMBL29215007 | 0.79 | TSHR (0.60) | SMN1; SMN2LMNATP53ALDH1A1KDM4E | |
| SCHEMBL33252 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2TP53ALDH1A1KDM4ETRPM8 | |
| SCHEMBL306847 | 0.79 | HPGD (0.54) | SMN1; SMN2TP53ALDH1A1KDM4ETRPM8 | |
| SCHEMBL29898808 | 0.79 | KMT2A (0.54) | SMN1; SMN2ALDH1A1MLYCDGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549015-B | Preparation method and application of 4-substituted phthalazinone derivative | 安徽工业大学 | 2023-07-14 | — | — | CN | disclosed |
| CN-113549015-A | Preparation method and application of 4-substituted phthalazinone derivative | 安徽工业大学 | 2021-10-26 | — | — | CN | disclosed |