Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.56 |
| ▸ | CFTR | P13569 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17064947 | 0.84 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL12261019 | 0.84 | MMP2 (0.53) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL15938456 | 0.83 | TSHR (0.55) | ALDH1A1HSD17B10KDM4EMAPTGAA | |
| SCHEMBL12347521 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL21786203 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL538290 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL30598338 | 0.80 | SMN1; SMN2 (0.55) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL22570384 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CFTRKDM4EMAPT | |
| SCHEMBL4611372 | 0.79 | KMT2A (0.53) | ALDH1A1HPGDPOLBTSHRRAB9A | |
| SCHEMBL28636864 | 0.79 | SMN1; SMN2 (0.40) | ALDH1A1HSD17B10CFTRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12391664-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | EMORY UNIVERSITY (US) | 2025-08-19 | — | — | US | disclosed |
| US-20240294493-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | UNIV EMORY (US) | 2024-09-05 | — | — | US | disclosed |
| CN-118439995-A | Preparation method of pitavastatin intermediate 3- [ 2-cyclopropyl-4- (4-fluorophenyl) -3-quinolyl ] -2-acrolein | 浙江工业大学 | 2024-08-06 | — | — | CN | disclosed |
| US-11981652-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | EMORY UNIVERSITY (US) | 2024-05-14 | — | — | US | disclosed |
| US-20210017149-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | UNIV EMORY (US) | 2021-01-21 | — | — | US | disclosed |
| US-20210017149-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | UNIV EMORY (US) | 2021-01-21 | — | — | US | disclosed |
| US-10730833-B2 | Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-08-04 | — | — | US | disclosed |
| US-20180222861-A1 | SYNTHESIS OF DIINDOLYLMETHANES AND INDOLO[3,2-B]CARBAZOLES, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-08-09 | — | — | US | disclosed |
| US-20180222861-A1 | SYNTHESIS OF DIINDOLYLMETHANES AND INDOLO[3,2-B]CARBAZOLES, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-08-09 | — | — | US | disclosed |
| US-9969686-B2 | Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2018-05-15 | — | — | US | disclosed |
| EP-1655289-A1 | Quinazoline derivatives, process for their preparation, their use as antimitotics and pharmaceutical compositions comprising said derivatives | EMBL (DE) | 2006-05-10 | — | — | EP | disclosed |
| EP-0979227-B1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA PHARMACEUTICAL (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-6352982-B1 | TREATING DIABETES, OBESITY, OR INVETERATE DIARRHEA IN A MAMMAL WHICH COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF A COMPOUND OF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-03-05 | — | — | US | disclosed |
| US-6100254-A | Inhibitors of protein tyrosine kinases | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2000-08-08 | — | — | US | disclosed |
| WO-2000014073-A1 | BENZODIAZEPINONE DERIVATIVES, PREPARATION METHOD AND INTERMEDIATES THEREFOR, USE AS MEDICINES AND COMPOSITIONS | HOECHST MARION ROUSSEL (FR) | 2000-03-16 | — | — | WO | disclosed |
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1999019306-A2 | 2,3-BENZODIAZEPIN-2-ONE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF PROTEIN TYROSINE KINASES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-04-22 | — | — | WO | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |
| US-5136085-A | Reacting an anthranilic acid amide with a halobenzene | GLAXO INC. (US) | 1992-08-04 | — | — | US | disclosed |
| US-5053543-A | Synthesis of 2-aminobenzophenones | GLAXO INC. (US) | 1991-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017149-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1693/4885HSD17B10 2979/4885CFTR 3811/4885 |
| US-20240294493-A1 | GluN2C/D Subunit Selective Antagonists of the N-Methyl-D-Aspartate Receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1930/4885HSD17B10 3000/4885CFTR 4314/4885 |
| US-10730833-B2 | Synthesis of diindolylmethanes and indolo[3,2-b]carbazoles, compounds formed thereby, and pharmaceutical compositions containing them | GLP1R, GIPR, INSR | ALDH1A1 4327/4885HSD17B10 961/4885CFTR 2380/4885 |
| US-12391664-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1930/4885HSD17B10 3000/4885CFTR 4314/4885 |
| US-11981652-B2 | GluN2C/D subunit selective antagonists of the N-methyl-D-aspartate receptor | GRIN2C, GRIN2A, GRIN2B | ALDH1A1 1930/4885HSD17B10 3000/4885CFTR 4314/4885 |
| US-20180222861-A1 | SYNTHESIS OF DIINDOLYLMETHANES AND INDOLO[3,2-B]CARBAZOLES, COMPOUNDS FORMED THEREBY, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLP1R, GIPR, INSR | ALDH1A1 4327/4885HSD17B10 961/4885CFTR 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.