Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22162847 | 1.00 | TDP1 (0.40) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL2074913 | 0.82 | GABRA1 (0.57) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL2074915 | 0.82 | GABRA1 (0.57) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL22123872 | 0.79 | TDP1 (0.37) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL22123873 | 0.79 | TDP1 (0.37) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL15772443 | 0.77 | ERN1 (0.61) | ERN1TSHRALDH1A1GAAHTT | |
| SCHEMBL15772442 | 0.77 | ERN1 (0.61) | ERN1TSHRALDH1A1GAAHTT | |
| SCHEMBL22162780 | 0.76 | GABRA1 (0.39) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL28632318 | 0.76 | GABRA1 (0.39) | TDP1ERN1GABRA1GABRG2GABRB3 | |
| SCHEMBL380731 | 0.75 | TDP1 (0.61) | TDP1ERN1ALDH1A1LMNAAMY1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113474348-A | Substituted oxopyridine derivatives | 拜耳公司 | 2021-10-01 | — | — | CN | disclosed |