Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074915 | 1.00 | GABRA1 (0.57) | GABRA1GABRG2GABRB3TDP1MAPT | |
| SCHEMBL28637138 | 0.82 | TDP1 (0.40) | GABRA1GABRG2GABRB3TDP1ALDH1A1 | |
| SCHEMBL22162847 | 0.82 | TDP1 (0.40) | GABRA1GABRG2GABRB3TDP1ALDH1A1 | |
| SCHEMBL15772442 | 0.80 | ERN1 (0.61) | MAPTALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL15772443 | 0.80 | ERN1 (0.61) | MAPTALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL2081028 | 0.80 | GABRA1 (0.51) | GABRA1GABRG2GABRB3TDP1MAPT | |
| SCHEMBL2081030 | 0.80 | GABRA1 (0.51) | GABRA1GABRG2GABRB3TDP1MAPT | |
| SCHEMBL21470208 | 0.77 | TYMS (0.37) | GABRA1GABRG2GABRB3TDP1MAPT | |
| SCHEMBL29028260 | 0.77 | GABRA1 (0.61) | GABRA1GABRG2GABRB3TDP1MAPT | |
| SCHEMBL8272588 | 0.77 | GABRA1 (0.61) | GABRA1GABRG2GABRB3TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414392-B | 6,7,8, 9-tetrahydro-5H-benzo [7] annulene-2-alkylamine compound and application thereof | 华东理工大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-108117534-A | The oxygen-containing cycloaliphatic ring methylamines of benzo | 华东理工大学 | 2018-06-05 | — | — | CN | disclosed |
| CN-108084125-A | Benzheterocycle alkyl amine compound and application thereof | 华东理工大学 | 2018-05-29 | — | — | CN | disclosed |
| CN-105566262-B | Alkyl amine compound of benzofuran 7 and application thereof | 华东理工大学 | 2017-10-27 | — | — | CN | disclosed |
| US-7897601-B2 | Cannabinoid receptor modulators | INTERVET, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897601-B2 | Cannabinoid receptor modulators | INTERVET, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897601-B2 | Cannabinoid receptor modulators | INTERVET, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| EP-1973877-A2 | CANNIBINOID RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2008-10-01 | — | — | EP | disclosed |
| US-20070197628-A1 | Cannabinoid receptor modulators | INTERVET INTERNATIONAL B.V. (NL) | 2007-08-23 | — | — | US | disclosed |
| US-20070197628-A1 | Cannabinoid receptor modulators | INTERVET INTERNATIONAL B.V. (NL) | 2007-08-23 | — | — | US | disclosed |
| US-20070197628-A1 | Cannabinoid receptor modulators | INTERVET INTERNATIONAL B.V. (NL) | 2007-08-23 | — | — | US | disclosed |
| WO-2007084450-A2 | CANNIBINOID RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007084450-A2 | CANNIBINOID RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197628-A1 | Cannabinoid receptor modulators | CNR1, CNR2, GPR18 | GABRA1 86/4885GABRG2 229/4885GABRB3 278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.