Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28632343 | 0.82 | KMT2A (0.53) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL3821816 | 0.78 | KMT2A (0.68) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL28636011 | 0.78 | KMT2A (0.58) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL28636007 | 0.74 | KMT2A (0.53) | KMT2AMEN1MTNR1BMTNR1ASIRT2 | |
| SCHEMBL28924753 | 0.74 | MEN1 (0.53) | KMT2AMEN1ALDH1A1PARP10PARP3 | |
| SCHEMBL28646238 | 0.74 | KMT2A (0.53) | KMT2AMEN1PARP10PARP3DRD1 | |
| SCHEMBL10081937 | 0.74 | KMT2A (0.58) | KMT2AMEN1KIF11MAPTALDH1A1 | |
| SCHEMBL11554638 | 0.73 | MEN1 (0.66) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL11191731 | 0.73 | KMT2A (0.66) | KMT2AMEN1GAAMAPTALDH1A1 | |
| SCHEMBL31092633 | 0.73 | AKR1C3 (0.42) | KMT2AMEN1SIRT2KIF11GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |