Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | PLAT | P00750 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28998392 | 0.85 | RAB9A (0.68) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28637154 | 0.82 | KMT2A (0.53) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2105853 | 0.81 | NPC1 (0.67) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13986887 | 0.79 | PTGS1 (0.65) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11191731 | 0.77 | KMT2A (0.66) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15651910 | 0.76 | HPSE (0.68) | KMT2ARAB9ATP53PKMMEN1 | |
| SCHEMBL28347463 | 0.76 | KMT2A (0.53) | KMT2ANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL9576738 | 0.75 | KMT2A (0.63) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL363882 | 0.75 | PTPN1 (0.67) | KMT2ANPC1RAB9AMEN1POLB | |
| SCHEMBL3821816 | 0.75 | KMT2A (0.68) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |