Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706311 | 0.86 | CYP3A4 (0.47) | KMT2AMEN1MTNR1AMTNR1BDRD1 | |
| SCHEMBL6540392 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1MTNR1AMTNR1BCHEK2 | |
| SCHEMBL3821816 | 0.78 | KMT2A (0.68) | KMT2AMEN1NPC1GAAMAPT | |
| SCHEMBL28636011 | 0.78 | KMT2A (0.58) | KMT2AMEN1PARP10PARP3NPC1 | |
| SCHEMBL6848984 | 0.74 | ALDH1A1 (0.47) | RAB9AALDH1A1MCL1SRCANXA2 | |
| SCHEMBL28646238 | 0.74 | KMT2A (0.53) | KMT2AMEN1PARP10PARP3DRD1 | |
| SCHEMBL28924753 | 0.74 | MEN1 (0.53) | KMT2AMEN1PARP10PARP3DRD1 | |
| SCHEMBL28637154 | 0.74 | KMT2A (0.53) | KMT2AMEN1MTNR1AMTNR1BPARP10 | |
| SCHEMBL10081937 | 0.74 | KMT2A (0.58) | KMT2AMEN1PARP10PARP3DRD1 | |
| SCHEMBL2727753 | 0.73 | ALDH5A1 (0.47) | NPC1MAPTRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476699-B | Glucocorticoid receptor agonists and immunoconjugates thereof | 艾伯维公司 | 2021-10-12 | — | — | CN | disclosed |