SCHEMBL28637181

SCHEMBL28637181

C1=Cc2ccccc21.O=c1c(O)coc2ccccc12

nearest known ligand 0.53

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOB P27338 15/20 0.53
MIF P14174 1/20 0.51
MAOA P21397 10/20 0.49
PTPN1 P18031 1/20 0.49
ADORA2B P29275 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL76091 0.91 MAOB (0.61) MAOBMIFMAOAPTPN1ADORA2B
Benzene SCHEMBL29096007 0.89 MAOB (0.62) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL276154 0.75 MAOB (0.48) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL72994 0.74 MIF (0.65) MAOBMIFMAOAPTPN1ADORA2B
Methane SCHEMBL28591261 0.73 MAOB (0.47) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL28864120 0.73 MAOB (0.47) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL4519275 0.70 MAOB (0.72) MAOBMAOAADORA2B
SCHEMBL27755477 0.70 MAOB (0.58) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL6557580 0.69 MAOB (1.00) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL11412845 0.69 KDM4E (0.65) MAOBMIFMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113354628-B 2-styryl-3-hydroxy chromone 2-thiophenecarboxylate fluorescent probe, preparation method and application thereof 南京林业大学 2021-12-28 CN claimed
CN-113354628-A 2-styryl-3-hydroxy chromone 2-thiophenecarboxylate fluorescent probe, preparation method and application thereof 南京林业大学 2021-09-07 CN claimed
CN-113354628-B 2-styryl-3-hydroxy chromone 2-thiophenecarboxylate fluorescent probe, preparation method and application thereof 南京林业大学 2021-12-28 CN disclosed
CN-113354628-B 2-styryl-3-hydroxy chromone 2-thiophenecarboxylate fluorescent probe, preparation method and application thereof 南京林业大学 2021-12-28 CN disclosed
CN-113354628-A 2-styryl-3-hydroxy chromone 2-thiophenecarboxylate fluorescent probe, preparation method and application thereof 南京林业大学 2021-09-07 CN disclosed
CN-113354628-A 2-styryl-3-hydroxy chromone 2-thiophenecarboxylate fluorescent probe, preparation method and application thereof 南京林业大学 2021-09-07 CN disclosed