SCHEMBL76091

SCHEMBL76091

O=c1c(O)coc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAOB P27338 12/20 0.61
MIF P14174 1/20 0.58
MAOA P21397 9/20 0.56
PTPN1 P18031 1/20 0.56
ADORA2B P29275 3/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
GLA P06280 1/20 0.50
CYP3A4 P08684 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
PGAM1 P18669 1/20 0.50
CASP1 P29466 1/20 0.50
CASP7 P55210 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
HSD17B10 Q99714 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL29096007 0.98 MAOB (0.62) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL28637181 0.91 MAOB (0.53) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL276154 0.82 MAOB (0.48) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL72994 0.81 MIF (0.65) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL28864120 0.80 MAOB (0.47) MAOBMIFMAOAPTPN1ADORA2B
Methane SCHEMBL28591261 0.80 MAOB (0.47) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL27755477 0.77 MAOB (0.58) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL11412845 0.76 KDM4E (0.65) MAOBMIFMAOAKDM4EALDH1A1
SCHEMBL6557580 0.76 MAOB (1.00) MAOBMIFMAOAPTPN1ADORA2B
SCHEMBL294155 0.75 MAOB (0.56) MAOBMIFMAOAPTPN1ADORA2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 145 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117580504-A Paper-based sensor 新加坡科技研究局 2024-02-20 CN claimed
US-8404088-B2 Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral bronsted acids TRUSTEES OF BOSTON UNIVERSITY (US) 2013-03-26 US claimed
US-20120238766-A1 ASYMMETRIC SYNTHESIS OF ROCAGLAMIDES VIA ENANTIOSELECTIVE PHOTOCYCLOADDITION MEDIATED BY CHIRAL BRONSTED ACIDS TRUSTEES OF BOSTON UNIVERSITY (US) 2012-09-20 US claimed
US-8137509-B2 Asymmetric synthesis of rocaglamides via enantioselective photocycloaddition mediated by chiral brønsted acids TRUSTEES OF BOSTON UNIVERSITY (US) 2012-03-20 US claimed
WO-2011140334-A2 COMPOUNDS, METHODS OF MAKING OR IDENTIFYING COMPOUNDS, AND USES THEREOF TRUSTEES OF BOSTON UNIVERSITY (US) 2011-11-10 WO claimed
US-7816544-B2 Synthesis of rocaglamide natural products via photochemical generation of oxidopyrylium species TRUSTEES OF BOSTON UNIVERSITY (US) 2010-10-19 US claimed
US-20090299081-A1 Asymmetric Synthesis of Rocaglamides via Enantioselective Photocycloaddition Mediated by Chiral Bronsted Acids TRUSTEES OF BOSTON UNIVERSITY (US) 2009-12-03 US claimed
US-20080265176-A1 COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-30 US claimed
US-20080177093-A1 Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species TRUSTEES OF BOSTON UNIVERSITY 2008-07-24 US claimed
EP-1866842-A2 A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM General Electric Company (US) 2007-12-19 EP claimed
WO-2007139749-A2 ASYMMETRIC SYNTHESIS OF ROCAGLAMIDES VIA ENANTIOSELECTIVE PHOTOCYCLOADDITION MEDIATED BY CHIRAL BRONSTED ACIDS TRUSTEES OF BOSTON UNIVERSITY (US) 2007-12-06 WO claimed
CN-1300163-C 3-hydroxy-chromogen ketoside and its preparation and use NANJING UNIVERSITY OF TECHNOLOGY (CN) 2007-02-14 CN claimed
WO-2006065561-A2 A COMPOSITION, METHOD OF AUTHENTICATING, METHODS OF MAKING AUTHENTICATABLE COMPOSITIONS, AUTHENTICATABLE ARTICLES MADE THERE FROM GENERAL ELECTRIC COMPANY (US) 2006-06-22 WO claimed
US-20060131761-A1 Composition, method of authenticating, methods of making authenticatable compositions, authenticatable articles made there from SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2006-06-22 US claimed
WO-2005092876-A1 SYNTHESIS OF ROCAGLAMIDE NATURAL PRODUCTS VIA PHOTOCHEMICAL GENERATION OF OXIDOPYRYLIUM SPECIES TRUSTEES OF BOSTON UNIVERSITY (US) 2005-10-06 WO claimed
CN-1594345-A 3-hydroxy-chromogen ketoside and its preparation and use NANJING UNIVERSITY OF TECHNOLOGY (CN) 2005-03-16 CN claimed
JP-55111410-A None JP disclosed
JP-55143908-A None JP disclosed
JP-S55111410-A COSMETIC FOR MAKING FAIR SKIN SANSHO SEIYAKU KK 1980-08-28 JP disclosed
US-4127669-A [(4-Oxo-4H-1-benzopyran-3-yl)oxy] acetic acids and derivatives WARNER-LAMBERT COMPANY (US) 1978-11-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299081-A1 Asymmetric Synthesis of Rocaglamides via Enantioselective Photocycloaddition Mediated by Chiral Bronsted Acids NFKBIA, NFKB1, NFE2L2 MAOB 1848/4885MIF 2127/4885MAOA 1855/4885
US-20120238766-A1 ASYMMETRIC SYNTHESIS OF ROCAGLAMIDES VIA ENANTIOSELECTIVE PHOTOCYCLOADDITION MEDIATED BY CHIRAL BRONSTED ACIDS NFKBIA, NFKB1, NFE2L2 MAOB 1848/4885MIF 2127/4885MAOA 1855/4885
US-20080177093-A1 Synthesis of Rocaglamide Natural Products Via Photochemical Generation of Oxidopyrylium Species NFKBIA, NFE2L2, NFKB1 MAOB 1308/4885MIF 4314/4885MAOA 1402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.