Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 8/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28864120 | 0.98 | MAOB (0.47) | MAOBMIFCA12CA1CA9 | |
| Methane SCHEMBL28591261 | 0.98 | MAOB (0.47) | MAOBMIFCA12CA1CA9 | |
| SCHEMBL76091 | 0.82 | MAOB (0.61) | MAOBMIFMAOAPTPN1ADORA2B | |
| Benzene SCHEMBL29096007 | 0.81 | MAOB (0.62) | MAOBMIFMAOAPTPN1ADORA2B | |
| SCHEMBL11573719 | 0.76 | MIF (0.49) | MAOBMIFMAOAPTPN1SIRT1 | |
| SCHEMBL7052888 | 0.74 | KDM4E (0.55) | PTPN1 | |
| SCHEMBL2490828 | 0.74 | CHRM2 (0.50) | MAOBMIFMAOAPTPN1CA2 | |
| SCHEMBL72994 | 0.72 | MIF (0.65) | MAOBMIFMAOAPTPN1ADORA2B | |
| SCHEMBL1110891 | 0.72 | ESR1 (0.56) | MAOBMIFCA12MAOASIRT1 | |
| SCHEMBL4247045 | 0.71 | KDM4E (0.54) | MAOBMIFCA12MAOAFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108610313-A | A kind of enzyme inhibitor and its application | 三峡大学 | 2018-10-02 | — | — | CN | claimed |
| WO-2016154694-A1 | N-ACYLHYDRAZONE COMPOUNDS INHIBITING HISTONE DESACETYLASE ENZYMES, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PRODUCING SAME | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO-UFRJ (BR) | 2016-10-06 | — | — | WO | claimed |
| CN-101830872-A | Synthetic method of 3-hydroxyl benzofuran derivatives | UNIV SOUTHERN MEDICAL | 2010-09-15 | — | — | CN | claimed |
| US-20040086983-A1 | Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase | MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) | 2004-05-06 | — | — | US | claimed |
| EP-0465254-B1 | Fused thiophene compounds and uses thereof | YOSHITOMI PHARMACEUTICAL (JP) | 1996-11-13 | — | — | EP | claimed |
| EP-0436199-B1 | Cyclopropyl derivative lipoxygenase inhibitors | ABBOTT LAB (US) | 1994-08-03 | — | — | EP | claimed |
| EP-0436199-A1 | Cyclopropyl derivative lipoxygenase inhibitors | ABBOTT LABORATORIES (US) | 1991-07-10 | — | — | EP | claimed |
| CN-117712481-A | Electrolyte, secondary battery and electric equipment | 华南理工大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-114524837-B | Condensed-cyclic compound containing boron nitrogen and dendritic structure, preparation method and application thereof, and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023100589-A1 | FLUORO RUBBER CROSSLINKING COMPOSITION AND MOLDED ARTICLE | ダイキン工業株式会社 | 2023-06-08 | — | — | WO | disclosed |
| CN-114524837-A | Condensed ring compound containing boron nitrogen and dendritic structure, preparation method and application thereof, and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2022-05-24 | — | — | CN | disclosed |
| WO-2022068772-A1 | BENZIMIDAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 深圳信立泰药业股份有限公司 | 2022-04-07 | — | — | WO | disclosed |
| CN-112851700-A | Condensed ring compound containing boron atom, oxygen atom and five-membered aromatic heterocycle and organic electroluminescent device | 中国科学院长春应用化学研究所 | 2021-05-28 | — | — | CN | disclosed |
| EP-0551662-A1 | Benzofuranyl- and thiophenylmethylthio-alcanecarboxylic acid derivatives | BAYER AG (DE) | 1993-07-21 | — | — | EP | disclosed |
| EP-0155574-B1 | PYRIDINIUM SALTS AND FUNGICIDES AND BACTERICIDES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1988-08-24 | — | — | EP | disclosed |
| EP-0094566-B1 | DIBENZOFURANYLOXYALKANE-IMIDAZOLIUM SALTS, PROCESS FOR THEIR PREPARATION AND THEIR MICROBICIDAL APPLICATION | BASF Aktiengesellschaft (DE) | 1986-03-12 | — | — | EP | disclosed |
| EP-0057362-B1 | DIBENZOFURANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF Aktiengesellschaft (DE) | 1984-06-20 | — | — | EP | disclosed |
| EP-0103277-A1 | Quaternary ammonium salts of benzofuran derivatives and fungicides containing them | BASF Aktiengesellschaft (DE) | 1984-03-21 | — | — | EP | disclosed |
| EP-0094566-A1 | Dibenzofuranyloxyalkane-imidazolium salts, process for their preparation and their microbicidal application | BASF Aktiengesellschaft (DE) | 1983-11-23 | — | — | EP | disclosed |
| US-4036982-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |