Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.96 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | VCP | P55072 | 2/20 | 0.42 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123351 | 0.92 | RAD52 (0.82) | RAD52SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL17484499 | 0.90 | RAD52 (0.79) | RAD52SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL20124124 | 0.87 | RAD52 (0.81) | RAD52SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL14302740 | 0.84 | RAD52 (0.70) | RAD52SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL3446318 | 0.82 | RAD52 (0.72) | RAD52SIGMAR1CHRM5SMN1; SMN2HTT | |
| SCHEMBL12838201 | 0.77 | RAD52 (0.60) | RAD52SIGMAR1VCPSMN1; SMN2 | |
| SCHEMBL7511582 | 0.77 | RAD52 (0.61) | RAD52SIGMAR1CXCR4SMN1; SMN2KMT2A | |
| SCHEMBL21549043 | 0.77 | RAD52 (0.66) | RAD52SIGMAR1HSD17B10VCPSMN1; SMN2 | |
| SCHEMBL24352354 | 0.76 | RAD52 (0.59) | RAD52SIGMAR1CHRM5CHRM3HSD17B10 | |
| SCHEMBL1321471 | 0.76 | RAD52 (0.64) | RAD52SMN1; SMN2KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016069-B | Tanshinone IIA piperazine compound and preparation method and application thereof | 上海星叶医药科技有限公司 | 2021-09-24 | — | — | CN | disclosed |