SCHEMBL12838201

SCHEMBL12838201

C1CCN(CCNC2CC2)C1

nearest known ligand 0.60

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAD52 P43351 1/20 0.60
CARM1 Q86X55 3/20 0.50
PRMT6 Q96LA8 3/20 0.50
PRMT8 Q9NR22 2/20 0.50
SIGMAR1 Q99720 1/20 0.50
HRH3 Q9Y5N1 3/20 0.40
CYP2C9 P11712 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
VCP P55072 1/20 0.39
PRMT1 Q99873 1/20 0.39
DPP7 Q9UHL4 1/20 0.37
CYP1A2 P05177 1/20 0.36
BCHE P06276 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4281737 0.98 RAD52 (0.63) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL3446318 0.91 RAD52 (0.72) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL3605906 0.87 RAD52 (0.53) RAD52CARM1PRMT6PRMT8SIGMAR1
Hydrochloric Acid SCHEMBL3598388 0.86 RAD52 (0.51) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL3585953 0.86 RAD52 (0.51) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL4649100 0.86 RAD52 (0.51) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL24333102 0.84 RAD52 (0.59) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL20402780 0.84 RAD52 (0.50) RAD52CARM1PRMT6PRMT8SIGMAR1
Hydrochloric Acid SCHEMBL4884203 0.84 RAD52 (0.50) RAD52CARM1PRMT6PRMT8SIGMAR1
SCHEMBL19953758 0.82 RAD52 (0.52) RAD52CARM1PRMT6PRMT8SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011035941-A1 LYSINE SPECIFIC DEMETHYLASE-1 INHIBITORS AND THEIR USE ORYZON GENOMICS S.A. (ES) 2011-03-31 WO disclosed