SCHEMBL28637433

SCHEMBL28637433

COC(=O)C(N)Cc1cccc(C)c1

nearest known ligand 0.54

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 6/20 0.54
ALDH1A1 P00352 2/20 0.50
POLB P06746 1/20 0.50
IDO1 P14902 2/20 0.45
MAOB P27338 2/20 0.44
NOS3 P29474 1/20 0.44
NOS1 P29475 1/20 0.44
NOS2 P35228 1/20 0.44
F10 P00742 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6218675 1.00 SLC7A5 (0.54) SLC7A5ALDH1A1POLBIDO1MAOB
SCHEMBL19699296 1.00 SLC7A5 (0.54) SLC7A5ALDH1A1POLBIDO1MAOB
Hydrochloric Acid SCHEMBL32677180 0.98 SLC7A5 (0.52) SLC7A5ALDH1A1POLBIDO1MAOB
Hydrochloric Acid SCHEMBL32676955 0.98 SLC7A5 (0.52) SLC7A5ALDH1A1POLBIDO1MAOB
Hydrochloric Acid SCHEMBL32676895 0.98 SLC7A5 (0.52) SLC7A5ALDH1A1POLBIDO1MAOB
SCHEMBL27762534 0.88 ALDH1A1 (0.50) SLC7A5ALDH1A1POLBIDO1MAOB
SCHEMBL20543766 0.88 ALDH1A1 (0.50) SLC7A5ALDH1A1POLBIDO1MAOB
SCHEMBL21117864 0.88 ALDH1A1 (0.50) SLC7A5ALDH1A1POLBIDO1MAOB
SCHEMBL13344379 0.86 MAOB (0.61) ALDH1A1POLBMAOB
SCHEMBL28940615 0.85 TAAR1 (0.47) ALDH1A1POLBIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113692401-A Process for producing aromatic amino acid derivative 中外制药株式会社 2021-11-23 CN disclosed
CN-108569974-B Method for synthesizing m-alkyl phenylalanine methyl ester derivative through palladium and norbornene co-catalysis 江西师范大学 2021-10-01 CN disclosed
CN-108569974-A Method for synthesizing m-alkyl phenylalanine methyl ester derivative through palladium and norbornene co-catalysis 江西师范大学 2018-09-25 CN disclosed